When most people hear the word, “arthritis”, they think of swollen and painful joints associated with old age. While that is one type of this disease, it is caused by wear and tear on the body over a period of time. Rheumatoid arthritis (RA), on the other hand, can strike as early as childhood and is actually an auto-immune disorder.
Unlike osteoarthritis, the causes of RA remain somewhat of a mystery. It is known to affect mainly people of middle age, though it has been recorded in people of all ages including infants. Women are more prone to this condition than men. Possible links have been made to certain types of infections, genetic causes, and different hormone levels, though none can be pointed to and named a definite cause.
Its effects can be readily identified, however. The body’s immune system begins to attack the healthy tissues in and around the joints. This leads to swelling, pain, fever in the affected joints, and eventual destruction of the joints. Unlike osteoarthritis, RA tends to affect both sides of the body equally. OA usually is worst on the dominant side because these joints are moved more and wear out quicker.
For the most part, medical treatment for rheumatoid arthritis has been based on symptoms experienced. Non-steroidal, anti-inflammatory drugs (NSAIDS) have long been prescribed to reduce the swelling in the joints. These medications also reduce the pain associated with the disease. However, the entire NSAID class of drugs has come under fire in recent years because of links to heart disease and increased risk of stroke if taken over a long period. They are also known to irritate the stomach, possibly leading to ulcers, if taken without food.
Corticosteroids have also been used with success to reduce swelling. However, they pose a risk of serious long-term side-effects if used continuously over a period of time. Therefore, the frequency and dosage are kept as low as possible.
Another class of drugs, Disease Modifying Anti-rheumatic Drugs (DMARDs) has been used to help reduce the symptoms and slow the progress of rheumatoid arthritis. The most common is methotrexate, though there some other medications in this category that may be prescribed. These drugs pose a serious potential for bad side effects. Therefore, doctors require blood tests at frequent intervals to ensure no problems develop related to them.
A new class of drugs, biologic agents, has recently been introduced. These medications are given in the form of injections at regular intervals. While these have been used with high success rates, they do pose some serious risks for patients. They directly affect the immune system, making the patient more prone to certain serious infections. They may also increase the risk of developing lymphoma or other types of cancer.
Aside from drug therapies to treat rheumatoid arthritis, patients are normally advised to take moderate exercise in order to keep the joints flexible. Over time, it is possible that some joints may become so severely damaged that one needs surgery to restore function. The most common type is the removal of the lining tissue in the joints. The last alternative is total joint replacement.
Related eBooks







